• Endocrinol Nutr · Jun 2015

    Review

    Parenteral nutrition-associated liver disease and lipid emulsions.

    • Ana Zugasti Murillo, Estrella Petrina Jáuregui, and Javier Elizondo Armendáriz.
    • Sección de Nutrición Clínica y Dietética, Complejo Hospitalario de Navarra, Pamplona, España. Electronic address: ana.zugasti.murillo@cfnavarra.es.
    • Endocrinol Nutr. 2015 Jun 1; 62 (6): 285-9.

    AbstractParenteral nutrition-associated liver disease (PNALD) is a particularly important problem in patients who need this type of nutritional support for a long time. Prevalence of the condition is highly variable depending on the series, and its clinical presentation is different in adults and children. The etiology of PNALD is not well defined, and participation of several factors at the same time has been suggested. When a bilirubin level >2 mg/dl is detected for a long time, other causes of liver disease should be ruled out and risk factors should be minimized. The composition of lipid emulsions used in parenteral nutrition is one of the factors related to PNALD. This article reviews the different types of lipid emulsions and the potential benefits of emulsions enriched with omega-3 fatty acids.Copyright © 2014 SEEN. Published by Elsevier España, S.L.U. All rights reserved.

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