• Biodrugs · Jun 2012

    Belimumab: a guide to its use in systemic lupus erythematosus.

    • Lesley J Scott, Celeste B Burness, and Paul L McCormack.
    • Adis, Auckland, New Zealand.
    • Biodrugs. 2012 Jun 1;26(3):195-9.

    AbstractBelimumab (Benlysta®), a fully human recombinant IgG1λ monoclonal antibody that inhibits the binding of soluble B lymphocyte stimulator to B cells, is indicated for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) with a high degree of disease activity despite receiving standard therapy. In multinational trials, significantly more belimumab recipients than placebo recipients achieved an SLE Responder Index response at 52 weeks.

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