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Gan To Kagaku Ryoho · Dec 2008
[Clinical effectiveness of anti-cholinergic agents for respiratory impediment in the home palliative care setting].
- Mitsuhiro Endo, Takeshi Toya, Tsutomu Matsumoto, Hirotoshi Maeda, and Tadashi Wada.
- Aozora Clinic, Shinmatsudo.
- Gan To Kagaku Ryoho. 2008 Dec 1;35 Suppl 1:19-21.
AbstractDyspnea is one of the most common problems we encounter in the palliative care setting of patients with life-threatening illness including malignancy. Dyspnea is considered especially a troublesome symptom in the management of in-home hospice care services. We examined effects of anti-cholinergic agents against such symptoms associated with dyspnea in patients with serious illness treated at home. The effectiveness was observed in 51% of patients who were given anti-cholinergic drugs. According to the outcome of this study, anti-cholinergic drugs may be effective for alleviating the suffering of terminally-ill patients due to dyspnea. Further investigation would be expected to clarify the usefulness of anti-cholinergic agents in the field of palliative care.
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