• Der Anaesthesist · Apr 2014

    Review

    [Interaction of anesthetics and analgesics with tumor cells.]

    • A Bundscherer, M Malsy, D Bitzinger, and B M Graf.
    • Klinik für Anästhesiologie, Universitätsklinikum Regensburg, Franz Josef Strauß Allee 11, 93053, Regensburg, Deutschland, anika.bundscherer@ukr.de.
    • Anaesthesist. 2014 Apr 1;63(4):313-25.

    AbstractThe results of preclinical and clinical studies indicate that the perioperative period is a vulnerable period for cancer progression and metastasis. The risk of cancer cell dissemination is enhanced by the combination of surgical manipulation and perioperative immunosuppression. Whether the oncological outcome of cancer patients can be influenced by the choice of anesthetic techniques is still a matter of debate. This review summarizes the molecular characteristics of cancer and interaction of anesthetic and analgesic drugs with cancer cells.

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