• E Domenegati, L Rolandi, L Lodola, M A Bressan, P Ceriana, and P Filisetti.
• I Servizio di Anestesia e Rianimazione, IRCCS Policlinico S. Matteo, Pavia.
• Minerva Anestesiol. 1996 Sep 1;62(9):297-305.

ObjectivesTo verify the results of a health surveillance protocol for personnel exposed to inhalation anaesthetics.DesignYearly follow-up of operating room personnel.SettingOperating theatres of a university hospital; one "clean" room with waste anaesthetic scavengers, a second older room an thus "dirty", a third room with appropriate technical requirements, but with a considerable environmental emission of anaesthetics.Patients Or ParticipantsTwenty-four technical surgical assistants and anaesthesiologists. INTERVENTION OR METHODS: Determination of the number of changes of air by means of concentration decay; determination of the baseline and final value of the environmental anaesthetics by infrared photoacoustic spectroscopy; analysis of the microclimate and inspection of the equipment. Determination of anaesthetics in the urine of personnel at the end of the work shift, using a gas-chromatograph with head space. Yearly medical check-up and blood tests.ResultsIn the first year of observation we found values of nitrous oxide in one room and of isoflurane in all three rooms which exceeded the upper limit value. Acceptable values in all the rooms were detected during the second year. The values of anaesthetics found in urine samples reflected those measured in the rooms. Personnel reported subjective symptoms, but no blood alterations related to exposure were found.ConclusionsThe application of the protocol has allow us to estimate the level of pollution and to suggest behavioral rules and technical precautions that have decreased the emission of anaesthetics in the environment. Blood tests are not a valid index of possible damage caused by exposure.

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