• Gan To Kagaku Ryoho · Mar 2015

    Case Reports

    [Case report of disseminated carcinomatosis of the bone marrow originating from gastric cancer with cancer-related disseminated intravascular coagulation successfully treated with recombinant human soluble thrombomodulin].

    • Hiroshi Kawamoto, Yoichiro Uchida, Shugo Ueda, Soshi Yanagita, and Hiroaki Terajima.
    • Dept. of Gastroenterological Surgery and Oncology, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital.
    • Gan To Kagaku Ryoho. 2015 Mar 1;42(3):363-5.

    AbstractA 62-year-old man, who underwent distal gastrectomy due to gastric cancer, was diagnosed with disseminated carcinomatosis of the bone marrow 8 years later. Chemotherapy was administered following treatment with recombinant human soluble thrombomodulin (rTM), and as a result, he successfully recovered from his disseminated intravascular coagulation (DIC) status and experienced improvement of his severe cancer-related pain. The use of rTM may enable the safe continuation of chemotherapy, and rTM may also be a useful treatment for DIC associated with solid cancer, such as gastric cancer.

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