-
Randomized Controlled Trial Comparative Study Clinical Trial
Gastric emptying: a study to compare the effects of intrathecal morphine and i.m. papaveretum analgesia.
- D W England, I J Davis, A E Timmins, R Downing, and C W Windsor.
- Department of Surgery, Worcester Royal Infirmary.
- Br J Anaesth. 1987 Nov 1;59(11):1403-7.
AbstractGastric emptying was studied in two groups of 10 patients who underwent elective cholecystectomy. The groups were comparable for age, weight and duration of operation. Gastric emptying was measured with a radioisotopic technique using Tc99m-DTPA (diethylene triamine pentaacetic acid) before, and 24 h after, surgery. Analgesia was provided by intrathecal morphine 0.8 mg alone (group A) or by i.m. papaveretum 10 mg, administered as required, plus one additional dose 1 h before the postoperative measurement (group B). Control gastric emptying rates were not significantly different in the two groups (mean +/- SD: A = 76.6 +/- 23.0 ml; B = 81.8 +/- 16.3 ml in 30 min). After surgery, gastric emptying was significantly greater in group A (42.9 +/- 35.6 ml) than in group B (11.0 +/- 27.9 ml) (P less than 0.05).
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