• Headache · Oct 2008

    Letter Case Reports

    Hemicrania continua evolving from cluster headache responsive to valproic acid.

    • Giorgio Lambru, Paola Castellini, Annamaria Bini, Andrea Evangelista, Gian Camillo Manzoni, and Paola Torelli.
    • Headache. 2008 Oct 1;48(9):1374-6.

    AbstractHemicrania continua (HC) is a rare type of primary headache characterized by a prompt and enduring response to indomethacin. We describe a patient who suffered from cluster headache evolving into ipsilateral HC, who does not tolerate a long-term indomethacin therapy. The case was complex in terms of diagnosis, associated comorbidity, and choice of treatment; after several trials with different therapeutic regimens, we started the patient on a therapy with valproic acid and obtained an improvement of her HC.

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