• Tayfun Apuhan, Yavuz Selim Yıldırım, Fadlullah Aksoy, Özlem Borçin, and Orhan Özturan.
• Abant Izzet Baysal University, Faculty of Izzet Baysal Medicine, Department of Otolaryngology, Bolu, Turkey.
• Int. J. Pediatr. Otorhinolaryngol. 2011 Jun 1;75(6):790-2.

ObjectiveTo compare the effects of, volatile anesthetics, desflurane and sevoflurane on intra-operative and postoperative bleeding in patients who underwent tonsillectomy and adenoidectomy.Material And MethodTotally 40 children (14 girl and 26 boys) aged between 2 and 16years were included in this prospective randomized double-blind clinical trial. The patients underwent conventional cold tonsillectomy and curettage adenoidectomy under general anesthesia. For the maintenance of anesthesia, the patients were randomized into two groups; desflurane group and sevoflurane group, each including 20 subjects. Desflurane concentration was set between 4% and 6% (0.7-0.9 MAC), whereas sevoflurane concentration was set between 2% and 2.5% (0.7-0.9 MAC). The amount of perioperative bleeding in milliliters was measured by using separate aspirator bags for each patient.ResultsDesflurane caused significantly lower amount of perioperative bleeding compared to sevoflurane (p=0.03). No significant difference was observed between the two groups in terms of age, body mass index and operation duration, respectively (p=0.20, p=0.49, p=0.07).ConclusionDesflurane, which is one of the volatile anesthetics, leads to a lower amount of intraoperative bleeding than sevoflurane during tonsillectomy and adenoidectomy operations.Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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