• Jesús Benito-Penalva, Dylan J Edwards, Eloy Opisso, Mar Cortes, Raquel Lopez-Blazquez, Narda Murillo, Ursula Costa, Jose M Tormos, Joan Vidal-Samsó, Josep Valls-Solé, European Multicenter Study about Human Spinal Cord Injury Study Group, and Josep Medina.
• Department of Spinal Cord Injury, Institut Guttmann, Hospital de Neurorehabilitació, Institut Universitari adscrit a la Universitat Autònoma de Barcelona, Barcelona, Spain. jbenito@guttmann.com
• Arch Phys Med Rehabil. 2012 Mar 1;93(3):404-12.

ObjectiveTo report the clinical improvements in spinal cord injury (SCI) patients associated with intensive gait training using electromechanical systems according to patient characteristics.DesignProspective longitudinal study.SettingInpatient SCI rehabilitation center.ParticipantsAdults with SCI (n=130).InterventionPatients received locomotor training with 2 different electromechanical devices, 5 days per week for 8 weeks.Main Outcome MeasuresLower-extremity motor score, Walking Index for Spinal Cord Injury, and 10-meter walking test data were collected at the baseline, midpoint, and end of the program. Patients were stratified according to the American Spinal Injury Association (ASIA) category, time since injury, and injury etiology. A subgroup of traumatic ASIA grade C and D patients were compared with data obtained from the European Multicenter Study about Human Spinal Cord Injury (EM-SCI).ResultsOne hundred and five patients completed the program. Significant gains in lower-limb motor function and gait were observed for both types of electromechanical device systems, to a similar degree. The greatest rate of improvement was shown in the motor incomplete SCI patients, and for patients <6 months postinjury. The positive response associated with training was not affected by injury etiology, age, sex, or lesion level. The trajectory of improvement was significantly enhanced relative to patients receiving the conventional standard of care without electromechanical systems (EM-SCI).ConclusionsThe use of electromechanical systems for intensive gait training in SCI is associated with a marked improvement in lower-limb motor function and gait across a diverse range of patients and is most evident in motor incomplete patients, and for patients who begin the regimen early in the recovery process.Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

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