-
- G H Caines and J H Goldstein.
- Department of Chemistry, Emory University, Atlanta, Georgia 30322.
- Magn Reson Med. 1987 Jul 1;5(1):67-72.
AbstractAggregation of human erythrocytes at physiological hematocrit by hydroxyethyl starch (HES) was investigated with a 1H nuclear magnetic resonance method which measures the erythrocyte mean water exchange time, tau a. A relationship that takes into account the effect of the aggregate as the water-exchanging unit was used to transform tau a values into the number of cells per aggregate, n. The procedure permits the determination of the time course of aggregation as well as its initial and equilibrium status. The values of n at equilibrium range from about 2 to 4 cells over the concentration of 1 to 5% HES in isotonic saline. The aggregation of erythrocytes in the presence of HES was found to follow first-order kinetics. The feasibility of this technique for application in the study of diseased states is indicated.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..