• Der Anaesthesist · Nov 1998

    Review

    [Sevoflurane in elderly patients].

    • W Reeker and E Kochs.
    • Institut für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München.
    • Anaesthesist. 1998 Nov 1; 47 Suppl 1: S58-62.

    AbstractAn ideal anaesthetic should allow rapid, pleasant, and predictable induction, maintenance and emergence from anaesthesia. Little information is available about sevoflurane use in elderly patients. The pharmacological profile of sevoflurane may be advantageous in geriatric patients because low solubility in the blood is a prerequisite for rapid changes in anaesthetic depth. In addition, the pharmacological profile of sevoflurane may help to reduce the total amount of drug required. Using volatile anaesthetics with low blood solubility and rapid clearance may help in an early postoperative assessment of the neurological status. Because geriatric patients show a higher intraoperative variability of haemodynamic parameters when compared to younger patients a drug such as sevoflurane with rapid uptake and elimination may be advantageous for treatment of hyper- and hypotensive states. As a consequence, the need for vasoactive drugs may be reduced. Recovery from sevoflurane anaesthesia is faster when compared with isoflurane. However, there is still controversy if the occurrence of postoperative cognitive and mental impairment is reduced in elderly patients if drugs with fast elimination characteristics are use. Few data are available on the use of sevoflurane in geriatric patients with renal impairment. Further studies are needed to clarify if the administration of sevoflurane is safe in this population of patients.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…