• Journal of critical care · Jun 2014

    Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients.

    • Chi-Min Park, Younsuck Koh, Kyeongman Jeon, Sungwon Na, Chae-Man Lim, Won-Il Choi, Young-Joo Lee, Seok Chan Kim, Gyu Rak Chon, Je Hyeong Kim, Jae Yeol Kim, Jaemin Lim, Chin Kook Rhee, Sunghoon Park, Ho Cheol Kim, Jin Hwa Lee, Ji Hyun Lee, Jisook Park, Juhee Cho, Shin Ok Koh, Gee Young Suh, Validation of Simplified acute physiology score 3 in Korean Intensive care unit (VSKI) study group, and Korean Study Group on Respiratory Failure (KOSREF).
    • Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
    • J Crit Care. 2014 Jun 1;29(3):409-13.

    IntroductionThis study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients.Materials And MethodsThis is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality.ResultsA total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (P<.001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer.ConclusionPreadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.Copyright © 2014 Elsevier Inc. All rights reserved.

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