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Annu Rev Public Health · Jan 1995
ReviewBayesian statistical methods in public health and medicine.
- R D Etzioni and J B Kadane.
- Fred Hutchinson Cancer Research Center, Seattle, Washington 98104, USA.
- Annu Rev Public Health. 1995 Jan 1;16:23-41.
AbstractThis article reviews the Bayesian statistical approach to the design and analysis of research studies in the health sciences. The central idea of the Bayesian method is the use of study data to update the state of knowledge about a quantity of interest. In study design, the Bayesian approach explicitly incorporates expressions for the loss resulting from an incorrect decision at the end of the study. The Bayesian method also provides a flexible framework for the monitoring of sequential clinical trials. We present several examples of Bayesian methods in practice including a study of disease progression in AIDS, a comparison of two therapies in a clinical trial, and a case-control study investigating the link between dietary factors and breast cancer.
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