• Cerebrovascular diseases · Jan 2009

    High resolution wall and lumen MRI of the middle cerebral arteries at 3 tesla.

    • Chang-Woo Ryu, Geon-Ho Jahng, Eui-Jong Kim, Woo-Suk Choi, and Dal-Mo Yang.
    • Department of Radiology, Kyunghee East-West Neo Medical Center, Kyunghee University, College of Medicine, Seoul, Korea. md.cwryu@gmail.com
    • Cerebrovasc. Dis. 2009 Jan 1;27(5):433-42.

    BackgroundAlthough black-blood MRI (BB-MRI) can identify plaques in the cervical carotid arteries, this modality has not been applied in intracranial arteries. We imaged the lumina and walls of stenotic middle cerebral arteries (MCAs) in symptomatic and asymptomatic patients using high-resolution BB-MRI, in order to characterize vulnerable plaques and to determine the diagnostic accuracy of BB-MRI in MCA stenosis.MethodsMulticontrast (T(1), T(2) and proton density)-weighted BB-MRIs were acquired in 15 patients with MCA stenosis and in 2 volunteers. Each MCA was classified into one of three groups based on MR angiographic findings and symptoms: normal, symptomatic stenosis, or asymptomatic stenosis. The plaque signal intensity was interpreted and the total wall thickness was measured at the most stenotic segment. These values were then compared between asymptomatic and symptomatic MCAs using t test. For assessment of lumen imaging, the MCA stenosis graded on BB-MR images was compared with that graded on conventional angiography (digital subtraction angiography).ResultsTwenty-eight MCAs were evaluated (normal MCAs: 12, symptomatic stenoses: 7, and asymptomatic stenoses: 9). T(1)- and/or T(2)-hyperintense foci were demonstrated more frequently within the plaques of symptomatic stenoses than within the plaques of asymptomatic stenoses (57.1 vs. 22%). The total wall thickness in the symptomatic stenoses was significantly higher than that seen in the asymptomatic stenoses. The stenosis grade for the BB-MRI was significantly correlated with the digital subtraction angiography grade.ConclusionHigh-resolution, multicontrast-weighted BB-MRI has the potential to characterize atherosclerotic plaques in the MCA and may be a useful modality for evaluating the degree of stenosis.Copyright 2009 S. Karger AG, Basel.

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