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- C Moretti, P Papoff, C S Barbàra, C Liberati, M Guidotti, and F Midulla.
- Department of Paediatrics, Paediatric Emergency and Intensive Care, Sapienza University of Rome, Rome, Italy. corrado.moretti@uniroma1.it
- Acta Biomed. 2013 Jan 1;84 Suppl 1:18-21.
AbstractIn children with acute lung injury the endogenous surfactant system is altered via a variety of different mechanisms, including inflammation, vascular dysfunction, oxidant injury, cellular injury and oedema. This article examines the pathophysiology of acute lung injury and surfactant use for treatment of acute respiratory failure in infants and children.
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