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J Laparoendosc Adv Surg Tech A · Apr 1999
Randomized Controlled Trial Clinical TrialNausea and vomiting after laparoscopic gynecologic surgery: a study of the incidence and the effects of tropisetron prophylaxis.
- J Jakobsson, G Dahlgren, E Oddby, and G Ryberg.
- Department of Anaesthesia, the Karolinska Institute, Danderyd Hospital and Sabbatsberg Närsjukhuset, Stockholm, Sweden.
- J Laparoendosc Adv Surg Tech A. 1999 Apr 1;9(2):141-5.
AbstractWe have studied the incidence of postoperative nausea and vomiting (PONV) and the effect of prophylactic tropisetron, a 5-HT3 antagonist, during the first 24 hr after elective gynecologic laparoscopic surgery. Thirty-two of 68 patients (47%) experienced nausea or vomiting some time during the observation period. Sixteen of these patients (50%) had their first emetic symptoms after discharge from the recovery room. We could see no difference in the frequency of PONV in the patients who were given prophylactic tropisetron 5 mg orally before anesthesia.
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