• Indian J Ophthalmol · Sep 2008

    Case Reports

    Retinal pigment epithelial atrophy following indocyanine green dye-assisted surgery for serous macular detachment.

    • Nazimul Hussain, Subhadra Jalali, Alka Rani, and Hema Rawal.
    • Smt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Hyderabad, India. nazimul@lvpei.org
    • Indian J Ophthalmol. 2008 Sep 1;56(5):423-5.

    AbstractTo report subretinal migration of indocyanine green dye (ICG) and subsequent retinal pigment epithelial (RPE) atrophy during macular surgery for serous macular detachment. A 65-year-old woman presented with residual epiretinal membrane and serous detachment of the macula following vitreoretinal surgery for epiretinal membrane. She underwent resurgery with ICG-assisted internal limiting membrane peeling and intraocular tamponade. Intraoperatively a large area of subretinal ICG was seen with subsequent RPE mottling and atrophy of the macula in the area involved during follow-up. This case demonstrates that subretinal migration of ICG is possible and can be toxic to RPE.

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