• Anesthesia and analgesia · Jun 2009

    Case Reports

    Vasoplegic syndrome during liver transplantation.

    • Zhongping Cao, Yuqi Gao, and Guocai Tao.
    • Department of Anesthesia, The Southwest Hospital of The Third Military Medical University, Chongqing, 400038, China.
    • Anesth. Analg. 2009 Jun 1;108(6):1941-3.

    AbstractA 56-yr-old woman with chronic hepatitis B and decompensated hepatic cirrhosis was treated with liver transplantation. At the beginning of the neohepatic phase, her arterial blood pressure remained at 60/40 mm Hg for approximately 40 min and did not respond to vasoconstrictive drugs. Her other clinical and laboratory values remained normal, apart from a high cardiac output and low systemic vascular resistance. This patient was diagnosed with vasoplegic syndrome and was treated with i.v. infusion of methylene blue (0.5 mg/kg) and norepinephrine. This report has potential significance to treatment in patients who undergo orthotopic liver transplantation.

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