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J Vet Emerg Crit Care (San Antonio) · Jan 2013
Case ReportsFalsely increased plasma lactate concentration due to ethylene glycol poisoning in 2 dogs.
- Kate Hopper and Steven E Epstein.
- Department of Veterinary Surgical and Radiological Sciences, University of California, Davis, CA 95616, USA. khopper@ucdavis.edu
- J Vet Emerg Crit Care (San Antonio). 2013 Jan 1;23(1):63-7.
ObjectiveTo describe false increases in plasma lactate concentration measured on point-of-care analyzers in 2 dogs with ethylene glycol (EG) intoxication.Case SummaryTwo dogs presenting with EG intoxication had extreme increases of plasma lactate concentrations recorded on a point-of-care machine. Laboratory analysis by spectrophotometry of lactate concentration determined these lactate measurements to be erroneous. False increases in plasma lactate concentration were demonstrated in 2 out of 3 point-of-care machines tested.New Or Unique Information ProvidedGlycolate, a toxic metabolite of EG, can interfere with the measurement of plasma lactate by some analyzers and this may delay the correct diagnosis of EG toxicity if not recognized.© Veterinary Emergency and Critical Care Society 2012.
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