• T Joseph, A Adeosun, T Paes, and V Bahal.
• Kettering General Hospital, Rothwell Road, Kettering NN16 8UZ, UK.
• Eur J Vasc Endovasc Surg. 2004 May 1;27(5):549-52.

ObjectiveSuture-hole bleeding is a considerable problem in vascular procedures using polytetrafluoroethylene (PTFE) grafts. This study aimed to study the efficacy of TachoComb H patches in controlling suture-hole bleeding.DesignProspective randomised controlled trial. Materials and methods. Patients undergoing femoral anastomosis and femoral or carotid patch angioplasty with PTFE grafts were prospectively randomised to TachoComb H patches or standard compression with surgical swabs.ResultsTwenty four patients were randomised (12 patients in each treatment group). The median time to haemostasis was 300 (range 180-600)s in patients treated with TachoComb H and 660 (range 180-1200)s in the control group. The log rank test of equality over treatments based on the 22 patients with assessment of time to haemostasis showed statistical significance (p=0.0134). There were no serious complications associated with use of TachoComb H patches.ConclusionTachoComb H patches were found to be safe and effective for the control of suture-hole bleeding in patients undergoing vascular reconstruction with PTFE grafts.

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