• Crit Care · Jun 2002

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    Cortisol replacement for severe sepsis and septic shock: what should I do?

    • Djillali Annane.
    • Intensive Care Department, Raymond Poincaré University Hospital, Garches, France. djillali.annane@rpc.ap-hop-paris.fr
    • Crit Care. 2002 Jun 1; 6 (3): 190-1.

    AbstractBased on several recently completed randomized controlled trials, cortisol replacement is likely to become a standard of care for vasopressor dependent septic shock. Further studies are needed in order to accomplish whether this treatment should be limited to patients with a blunted cortisol response to corticotrophin. Similarly, in patients with severe sepsis who do not need vasopressors, the benefit/risk ratio of cortisol replacement remains to be assessed.

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