• T Uchida, N Oka, M Aoki, A Taniguchi, M Yagi, and T Okada.
• Masui. 1989 Feb 1;38(2):246-52.

AbstractOne hundred healthy parturients scheduled for elective cesarean section were studied prospectively. Fifty patients received spinal anesthesia with 12mg of hyperbaric tetracaine and were defined as the spinal group. Other fifty patients received epidural anesthesia with 300mg of lidocaine and were defined as the epidural group. A half of patients in each group were given 1,000ml of Ringer's lactate immediately before the regional anesthesia (prehydrated). Rapid hydration was not given to another half of them (non-prehydrated). In the spinal group, ephedrine administration was needed significantly less frequently for prehydrated patients than for non-prehydrated ones. And the mean dose of this drug for prehydrated patients was significantly less than that for non-prehydrated ones. In the epidural group, though prehydration tended to prevent maternal hypotension, neither rate of ephedrine administration nor mean doses of this drug showed any significant difference between prehydrated and non-prehydrated patients. Prehydration did not improve significantly neither acid-base balances of umbilical arterial and venous blood nor Apgar scores of the neonates in either group. We conclude that massive fluid load is not indispensable immediately before the regional anesthesia for the parturient. Furthermore, because this method is not reliable, its advantages and disadvantages including the possibility of enhancing pulmonary edema should be evaluated.

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