-
- C Bradley.
- St. George's Hospital, London, UK.
- Intensive Crit Care Nurs. 2001 Aug 1;17(4):242-4.
AbstractEarly studies using high doses of steroids in septic shock resulted in increased mortality. More recently, work by Annane et al. using lower doses closer to those that might constitute a stress dose of hydrocortisone have shown encouraging results with a 30% decrease in mortality in septic shock. Although this result is more impressive than the reduction in mortality resulting from the use of activated protein C in septic shock, the numbers of patients involved in the steroid study are low and the results remain unpublished in a peer-reviewed journal.
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