• ASAIO J. · Jan 2013

    Case Reports

    Detection of carboxyhemefibrinogen and methemefibrinogen in a patient with thrombosis of a HeartMate II ventricular assist device.

    • M Cristina Smith and Vance G Nielsen.
    • Department of Surgery, The University of Arizona College of Medicine, Tucson, Arizona 85724-5114, USA.
    • ASAIO J. 2013 Jan 1;59(1):93-5.

    AbstractVentricular assist device (VAD) thrombosis is a devastating, potentially fatal complication suffered by patients requiring mechanical circulatory support. We present a patient with thrombosis of a HeartMate II VAD with concurrent hemolysis and increased carbon monoxide formation. Using a specialized thrombelastographic assay, we detected marked plasmatic hypercoagulability mediated in part by the formation of carboxyhemefibrinogen.

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