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Interact Cardiovasc Thorac Surg · Oct 2009
Case ReportsThe acute chest syndrome of sickle cell disease following aortic valve replacement.
- Bari Murtuza, Prity Gupta, and Kulvinder S Lall.
- Department of Cardiothoracic Surgery, St Bartholomew's Hospital, London EC1A 7BE, UK. b.murtuza@ic.ac.uk
- Interact Cardiovasc Thorac Surg. 2009 Oct 1;9(4):746-7.
AbstractThe acute chest syndrome (ACS) of sickle cell disease (SCD) is a leading cause of death in SCD, with a high incidence following surgery, though only one case has been reported following cardiac surgery. We present a case of ACS in an adult undergoing aortic valve replacement (AVR) despite instituting established peri-operative optimization measures to prevent sickling. Early diagnosis of this condition in our patient as a distinct clinical entity facilitated appropriate, specific therapy and a good subsequent postoperative recovery. Greater recognition of this syndrome in the growing number of adult sickle cell patients presenting for cardiac surgery may help improve their outcome.
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