• Nutr Clin Pract · Apr 2015

    Phase angle as a prognostic marker in patients with critical illness.

    • Taís Kereski da Silva, Marina Carvalho Berbigier, Bibiana de Almeida Rubin, Rafael Barberena Moraes, Gabriela Corrêa Souza, and Ingrid Dalira Schweigert Perry.
    • Multiprofessional Integrated Residency Program in Health, with emphasis on Critical Adults, Hospital de Clínicas de Porto Alegre, Brazil Food and Nutrition Research Center, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Brazil.
    • Nutr Clin Pract. 2015 Apr 1;30(2):261-5.

    BackgroundPhase angle (PA) is interpreted as an indicator of cell membrane integrity and a prognostic indicator in some clinical situations. This study aims to evaluate PA as a prognostic marker in critically ill patients admitted to the intensive care unit (ICU) and associate this marker with length of hospital stay, mortality, and clinical scores.MethodsA cohort study was conducted with 95 patients aged ≥18 years admitted to the ICU, who were assessed in terms of prognostic indexes (Acute Physiology and Chronic Health Evaluation II [APACHE II] and Sequential Organ Failure Assessment [SOFA]), clinical evolution (ICU discharge, death, and length of ICU stay), and PA.ResultsPatients were predominantly male (63.1%) and had a mean age of 63.7 ± 14.6 years; length of stay of 4 days (range, 3-9 days); mortality of 15.8%; mean APACHE II and SOFA scores of 17.3 ± 8.2 and 6.1 ± 3.1 points, respectively; and mean PA of 4.91 ± 1.36°. An association was observed between females and PA <5.1° (P = .035), which was the cutoff point determined from the receiver operating characteristic curve. PA was correlated with APACHE II score (r = -0.241; P = .02). This correlation became moderate only when patients without sepsis were considered (r = -0.506; P < .001).ConclusionsPA seems to be a good prognostic marker for patients without sepsis. The weak correlation between PA and APACHE II score and the lack of association with other clinical outcomes are limitations for interpreting the prognostic value of PA in the entire study sample.© 2015 American Society for Parenteral and Enteral Nutrition.

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