• Journal of neurosurgery · Feb 1996

    Case Reports

    Intrathecal granuloma complicating chronic spinal infusion of morphine. Report of three cases.

    • J P Blount, K B Remley, S K Yue, and D L Erickson.
    • Department of Neurosurgery and Radiology, University of Minnesota School of Medicine, St. Paul, USA.
    • J. Neurosurg. 1996 Feb 1;84(2):272-6.

    AbstractIntrathecal morphine delivered by implanted pumps has been used in the treatment of pain caused by terminal cancer. Some authors supports its use in benign pain as well. The authors present three cases in which chronic infiltration of intraspinal narcotic medication was complicated by the formation of a granulomatous mass that became large enough to exert mass effect and induce neurological dysfunction.

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