• Anaesthesia · Sep 1994

    Randomized Controlled Trial Clinical Trial

    Pain during injection of propofol. The effect of prior administration of thiopentone.

    • T W Lee, A E Loewenthal, J A Strachan, and B D Todd.
    • Department of Anaesthesia and Intensive Care, Townsville General Hospital, Queensland, Australia.
    • Anaesthesia. 1994 Sep 1;49(9):817-8.

    AbstractA controlled, double-blind study was performed to compare the prior administration of intravenous saline 4 ml (n = 36), lignocaine 20 mg (n = 36) or thiopentone 100 mg (n = 43) on the pain produced by intravenous injection of propofol. One hundred and fifteen ASA 1 or 2 patients scheduled for minor surgery were studied using a randomised, double-blind design. Thiopentone was more effective than lignocaine in reducing the incidence of propofol injection pain (p < 0.03).

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