Combined pallidal and subthalamic nucleus stimulation in

Journal of neurosurgery · Jan 2012

Case Reports

Combined pallidal and subthalamic nucleus stimulation in sporadic dystonia-parkinsonism.

Multifocal deep brain stimulation (DBS) is a new technique that has been introduced recently. A 39-year-old man with dystonia-parkinsonism underwent the simultaneous implantation of subthalamic nucleus (STN) and globus pallidus internus (GPi) DBS electrodes. ⋯ Formal assessment at the 1-year follow-up showed that both the parkinsonian symptoms and the dystonia were markedly improved via continuous bilateral combined STN and GPi stimulation. Sustained benefit was achieved at 3 years postoperatively.

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- Johannes C Wöhrle, Christian Blahak, Hans-Holger Capelle, Wolfgang Fogel, Hansjoerg Bäzner, and Joachim K Krauss.
- Department of Neurology, University Hospital Mannheim, Germany.
- J. Neurosurg. 2012 Jan 1;116(1):95-8.
AbstractMultifocal deep brain stimulation (DBS) is a new technique that has been introduced recently. A 39-year-old man with dystonia-parkinsonism underwent the simultaneous implantation of subthalamic nucleus (STN) and globus pallidus internus (GPi) DBS electrodes. While bilateral STN DBS controlled the parkinsonian symptoms well and allowed for a reduction in levodopa, the improvement of dystonia was only temporary. Additional GPi DBS also alleviated dystonic symptoms. Formal assessment at the 1-year follow-up showed that both the parkinsonian symptoms and the dystonia were markedly improved via continuous bilateral combined STN and GPi stimulation. Sustained benefit was achieved at 3 years postoperatively.

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Combined pallidal and subthalamic nucleus stimulation in sporadic dystonia-parkinsonism.

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