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- Darwin J Prockop and Joo Youn Oh.
- Institute for Regenerative Medicine, Texas A&M Health Science Center College of Medicine at Scott & White, Temple, Texas 76502, USA. Prockop@medicine.tamhsc.edu
- J. Cell. Biochem. 2012 May 1;113(5):1460-9.
AbstractThere is currently great interest in the use of mesenchymal stem/stromal cells (MSCs) for the therapy of many diseases of animals and humans. However, we are still left with the serious challenges in explaining the beneficial effects of the cells. Hence, it is essential to work backward from dramatic results obtained in vivo to the cellular and molecular explanations in order to discover the secrets of MSCs. This review will focus on recent data that have changed the paradigms for understanding the therapeutic potentials of MSCs.Copyright © 2011 Wiley Periodicals, Inc.
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