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- Eduardo Romay and Ricard Ferrer.
- Intensive Care Department, Mutua Terrassa University Hospital, Terrassa, Spain.
- Blood Purif. 2014 Jan 1;37 Suppl 1:18-21.
AbstractThe relentless increase in healthcare costs and the global economic crisis require us to rethink the way research is done. The heterogeneity of patients is a major challenge in designing and coordinating high-quality studies about sepsis. Studies on new treatments and devices, such as polymyxin B hemoperfusion, must be optimized not only for potential benefits for a specific population (i.e. efficacy), but also for their eventual implementation in real-world situations (i.e. effectiveness) and for economic costs (i.e. efficiency). In this regard, theragnosis and newer statistical tools could help us obtain useful information from real-life observational data. In this review, we discuss the basic components required for sustainable research in polymyxin B hemoperfusion.© 2014 S. Karger AG, Basel.
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