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Comparative Study
Conduction block of peripheral nerve using high-frequency alternating currents delivered through an intrafascicular electrode.
- D Michael Ackermann, Emily L Foldes, Niloy Bhadra, and Kevin L Kilgore.
- Case Western Reserve University, Cleveland, Ohio, USA.
- Muscle Nerve. 2010 Jan 1;41(1):117-9.
AbstractMany diseases are characterized by undesired or pathological neural activity. The local delivery of high-frequency currents has been shown to be an effective method for blocking neural conduction in peripheral nerves and may provide a therapy for these conditions. To date, all studies of high-frequency conduction block have utilized extraneural (cuff) electrodes to achieve conduction block. In this study we show that high-frequency conduction block is feasible using intrafascicular electrodes.
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