• Minerva anestesiologica · Sep 2016

    Time-dependent and independent neurophysiological indicators of prognosis in post-anoxic coma subjects treated by therapeutic hypothermia.

    • Riccardo Carrai, Antonello Grippo, Maenia Scarpino, Maddalena Spalletti, Cesarina Cossu, Giovanni Lanzo, Adriano Peris, Giovanni Cianchi, Stefano Batacchi, Serafina Valente, Gianfranco Gensini, and Aldo Amantini.
    • SODc Neurofisiopatologia, Dipartimento Neuromuscolo-Scheletrico e degli Organi di Senso, AOU Careggi, Florence, Italy - riccardo.carrai@unifi.it.
    • Minerva Anestesiol. 2016 Sep 1; 82 (9): 940-9.

    BackgroundEvaluation of prognostic value of electroencephalography (EEG) and somatosensory evoked potentials (SEP) according to different recording times.MethodsA retrospective cohort study performed at the medical ICU of the AOU Careggi Teaching Hospital (Florence, Italy) of comatose adults (>18 years) after cardiac arrest (CA) and treated with therapeutic hypothermia (TH). We evaluated the Glasgow Coma Scale, EEG, and SEP performed at 12, 24, and 72 hrs after CA. Outcome was determined by the Glasgow Outcome Scale at 6 months after CA.ResultsWe analyzed 167 patients. All patients with grade 1 EEG ("continuous") within 12 hours of CA recovered consciousness (false positive rate: 0.0%). Grade 2 EEG ("non-continuous") at 72 hours predicted a poor outcome with FPR=0.0%. Bilateral absent SEP at any time after CA predicted a poor outcome.ConclusionsEEG is a reliable time-dependent predictor of a good outcome (within 12 hours) and a poor outcome (after 72 hours). SEP is a time-independent predictor of a poor outcome.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…