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- Maria Pia De Carolis, Marco Piastra, Iliana Bersani, Manuela Pardeo, Eleonora Stival, Alessia Tempera, Costantino Romagnoli, Giorgio Conti, and Gabriella De Rosa.
- Neonatal ICU, Department of Pediatrics, Catholic University of the Sacred Heart, A. Gemelli Hospital, Rome, Italy. mpia.decarolis @ rm.unicatt.it
- Neonatology. 2012 Jan 1;101(3):201-5.
AbstractWe report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults.Copyright © 2011 S. Karger AG, Basel.
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