• Cengiz Mordeniz, Fuat Torun, Ahmet Faruk Soran, Orhan Beyazoglu, Hamza Karabag, Ahmet Cakir, and Seyho Cem Yucetas.
• Department of Anesthesiology, Faculty of Medicine, Harran University, Sanliurfa, Turkey. cengizmorster@gmail.com
• Arch Orthop Trauma Surg. 2010 Feb 1;130(2):205-8.

IntroductionThis is a prospective, non-randomized, hospital-based, case-controlled, clinical trial to assess the efficacy of perineural infiltration with bupivacaine at the related neural root for acute pain relief after lumbar laminectomy.MethodFifty-one patients undergoing unilateral one spinal level (lumbar 4) hemi-partial laminectomy were included in the study. In 22 of the patients (Group 2), bupivacaine was infiltrated onto the neural root immediately after the exposure; the 29 patients in the control group (Group 1) were not infiltrated. All patients were monitored post-operatively regarding pain determination using a visual analog scale, and the exact time of analgesic requirement during the first post-operative day was noted. Total analgesic dose given during the first post-operative day was also recorded.ResultsThe patients who received bupivacaine infiltration intraoperatively onto the neural root (Group 2) had a statistically significantly longer time to first analgesia request (P < 0.001) and also required significantly less analgesic when compared to the control group (Group 1) (P < 0.001). Perineural bupivacaine infiltration extended the early post-operative analgesic period. While the pain was not completely suppressed, the bupivacaine infiltration helped to manage the post-operative pain more effectively.ConclusionOur data suggests that pre-emptive analgesia via perineural infiltration of bupivacaine is a simple, and effective method for post-operative acute pain relief.

23 keywords...

hide…