• Cardiovasc Intervent Radiol · Nov 2008

    Case Reports

    Continuous intra-arterial nimodipine for the treatment of cerebral vasospasm.

    • Thomas E Mayer, Martin Dichgans, Andreas Straube, Tobias Birnbaum, Stephanie Müller-Schunk, Gerhard F Hamann, and Gernot Schulte-Altedorneburg.
    • Department of Neuroradiology, University Hospital, Friedrich-Schiller-University Jena, Erlanger Allee 101, Jena 07747, Germany. t.e.mayer@med.uni-jena.de
    • Cardiovasc Intervent Radiol. 2008 Nov 1;31(6):1200-4.

    AbstractTwo patients with refractory symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) were treated by continuous intra-arterial nimodipine infusion via a catheter placed in the internal carotid artery or vertebral artery for 3 and 12 days, respectively. Recovery of the neurological deficits, normalization of MR perfusion, a decrease in the elevated mean flow velocity measured by transcranial duplex sonography, and angiographic recanalization were observed. Continuous intra-arterial nimodipine might be a treatment option in severe refractory vasospasm following SAH.

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