• L Sarna.
• School of Nursing, University of California, Los Angeles, USA.
• Oncol Nurs Forum. 1998 Jul 1;25(6):1041-8.

Purpose/ObjectivesTo test the efficacy of structured symptom assessment on level and rate of change in symptom distress over time.DesignProspective six-month randomized control trial.SettingOutpatient oncology offices and clinics in California.Sample48 subjects newly diagnosed with advanced lung cancer, predominantly non-small cell. Most subjects received chemotherapy, 50% were women, and their average age was 62 years. 190 observations were analyzed.MethodsSubjects were assigned randomly to structured assessment or usual care. Both groups completed the Symptom Distress Scale (SDS) monthly. After bivariate screening of potential predictors, a multivariate regression model for level and rate of change in SDS scores was created.Main Research VariablesSymptom distress, functional status, and emotional distress.FindingsFatigue was the most common severely distressing symptom. In a multivariate model, chemotherapy and systematic assessment were associated with less symptom distress over time. Higher scores in depression and more functional limitations were related to higher levels of overall distress. Weight loss had a small impact.ConclusionsSystematic use of structured symptom assessment forestalled increased symptom distress over time. Chemotherapy lessened symptom distress, but the impact diminished with time. Subjects with more depression and greater functional limitations had greater symptom distress.Implications For Nursing PracticeDuring the course of advanced lung cancer, systematic ongoing nursing assessment of symptoms may be the first step in enhancing interventions to decrease distress. Patients at highest risk for symptom distress are those who experience emotional distress and functional limitations.

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