• Anesthesia and analgesia · Mar 2007

    Randomized Controlled Trial

    Intrathecal anesthesia for elderly patients undergoing short transurethral procedures: a dose-finding study.

    • Edna Zohar, Yossi Noga, Uri Rislick, Ilan Leibovitch, and Brian Fredman.
    • Department of Anesthesiology, Intensive Care and Pain Management, Meir Medical Center, Kfar Saba, Israel.
    • Anesth. Analg. 2007 Mar 1;104(3):552-4.

    AbstractOne hundred elderly men (> or =65 yr) undergoing transurethral procedures (<45 min) received bupivacaine 7.5 mg, or bupivacaine 5 mg + fentanyl 20 mug, or bupivacaine 4 mg + fentanyl 20 mug, or bupivacaine 3 mg + fentanyl 20 mug, intrathecally. Intraoperative "rescue" fentanyl requirements were higher (P < 0.03) in group bupivacaine 3 mg + fentanyl. Times (min) to ambulation eligibility were decreased in a dose-dependant manner (157 +/- 50 vs 147 +/- 37 vs 128 +/- 40 vs 116 +/- 29, respectively). Of the techniques studied, intrathecal bupivacaine 4 mg + fentanyl 20 mug provided adequate analgesia and was associated with hemodynamic stability and a favorable recovery profile.

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