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Case Reports
Intrapleural streptokinase for the treatment of complicated parapneumonic effusion and empyema in 2 newborns.
- Avidan Kizilelma Yigit, Yavuz Yilmaz, Omer Erdeve, Ismail Kursad Gokce, Serife Suna Oguz, Nurdan Uras, and Ugur Dilmen.
- Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, 06230 Ankara, Turkey. avidankizilelma@yahoo.com
- J. Pediatr. Surg. 2012 Oct 1;47(10):e41-4.
AbstractThe management of complicated parapneumonic effusions by conventional first-line treatment with closed intercostal tube drainage and antibiotic therapy may fail because of thick viscous fluid and multiple pleural space loculations. Intrapleural fibrinolytic treatment is a non-invasive therapeutic option. In this report, we present successful use of intrapleural streptokinase for complicated parapneumonic effusion and empyema in 2 newborns. Intrapleural fibrinolytic therapy with streptokinase appears to be a safe and effective adjunctive therapy of choice and may have significant benefit even in newborns with complicated parapneumonic effusion and empyema, and thus, it can obviate surgical intervention.Copyright © 2012 Elsevier Inc. All rights reserved.
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