• C Chaix, I Durand-Zaleski, C Alberti, and C Brun-Buisson.
• Department of Public Health, Henri Mondor Hospital AP-HP, Paris, France.
• Pharmacoeconomics. 1999 Jun 1;15(6):573-82.

ObjectiveOur objective was to identify, among the information routinely collected on patients in intensive care units (ICUs), data that determine the total cost for a given patient.DesignWe developed a model that could help physicians in medical ICUs to estimate the cost of care for their patients when no cost data were available at the individual patient level.SettingA Medical ICU.Patients And ParticipantsThe model was developed using a random sample of 73 patients admitted to the medical ICU in 1996 and 1997, validated by another random sample of 29 patients admitted during the same period.InterventionsThe actual medical variable cost per patient was computed from data on the total resources used (excluding personnel and fixed costs), collected from the patients' records plus pharmacy, laboratory and blood bank logs. The explanatory variables tested were: length of stay, nursing workload, severity of condition, and procedures recorded by a score [omega (omega)] including 3 components related to the frequency of procedure use. The model was constructed in a stepwise fashion, assuming a linear relation. Equations were tested on the basis of the residual mean square; criteria for inclusion and elimination of variables were the level of its partial regression coefficient and medical criteria. The model was validated by analysis of variance of the regression on a second population of 29 patients using the F-test.Main Outcome Measures And ResultsThe median length of stay was 7 days (range: 3 to 22 days). Mortality rate was 25%. Median medical variable cost was 805 Pounds (mean medical variable cost was 1738 Pounds, total cost was 6279 Pounds). The variables selected in the multiple regression model as relevant predictors of medical costs were: procedures recorded only once during the ICU stay irrespective of their reiteration (omega 1), procedures recorded every time they are performed (omega 2), procedures recorded daily in the ICU (omega 3) and the presence or absence of an invasive procedure (Kc). The final equation, calibrated with r2 of 0.826 and p > 0.0001, was: medical cost (Pounds) = 23 omega 1 + 53 omega 2 + 8 omega 3 + 2352Kc + 96. The validation with the other sample of 29 patients compared actual to predicted costs. Analysis of variance of the regression from the model was r2 = 0.596 (p > 0.05).ConclusionsOur standardised cost model is a possible approach to allow comparison of medical costs within and between ICUs.

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