• Nabil Hassan, Matthew Halanski, Jeni Wincek, Diann Reischman, Dominic Sanfilippo, Surender Rajasekaran, Cecilia Wells, Deborah Tabert, Beth Kurt, Deanna Mitchell, John Huntington, and Jeffrey Cassidy.
• Grand Valley State University, Allendale, Michigan, USA. nabil.hassan@helendevoschildrens.org
• Transfusion. 2011 Oct 1;51(10):2133-41.

BackgroundPediatric scoliosis surgery is associated with considerable blood loss and allogenic transfusions. Transfusions contribute to morbidities and cost. A perioperative pediatric blood management program was implemented at our institution. Patients received preoperative evaluation, cell salvage, topical hemostasis, antifibrinolytics, and hypotensive anesthesia.Study Design And MethodsThe study was a 2-year retrospective cohort review of the program's population from September 2007 through August 2009.ResultsA total of 110 scoliosis surgeries were performed with only 34 and 12% of the patients requiring preoperative oral iron and erythropoietin, respectively. Neuromuscular scoliosis patients had more repaired segments and a larger transfusion rate than idiopathic scoliosis patients (36% vs. 1.7%, p = 0.001). Transfused patients had more blood loss relative to their blood volume (p = 0.001) and blood loss was associated with higher Cobb angles (p = 0.04). Logistic regression revealed that blood loss (p = 0.001), number of segments fused (p = 0.004), and lower patient weight (p = 0.007) are associated with increased odds for transfusion. Twelve patients (10.9%) were identified with low von Willebrand activity with a trend toward higher blood losses (p = 0.07) with lower activity levels.ConclusionTransfusion requirements in scoliosis patients are dependent on blood loss as determined by Cobb angles and number of segments fused relative to the patients' blood volume as determined by weight. Implementation of a blood management protocol resulted in a low transfusion rate and unexpectedly led to the preoperative diagnosis of a number of patients with low levels of von Willebrand activity.© 2011 American Association of Blood Banks.

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