• Respiratory investigation · Mar 2016

    Case Reports

    High-flow nasal cannula oxygen therapy for acute exacerbation of interstitial pneumonia: A case series.

    • Yukihiro Horio, Takahisa Takihara, Kyoko Niimi, Masamichi Komatsu, Masako Sato, Jun Tanaka, Hiroto Takiguchi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Naoki Hayama, Tsuyoshi Oguma, Takuya Aoki, Tetsuya Urano, Atsushi Takagi, and Koichiro Asano.
    • Division of Pulmonary Medicine, Department of Medicine, Tokai University School of Medicine, Kanagawa, Japan. Electronic address: h_5amm1218@yahoo.co.jp.
    • Respir Investig. 2016 Mar 1; 54 (2): 125-9.

    AbstractWe report 3 cases (all men, age: 69-81 years) of acute exacerbation of interstitial pneumonia (AEIP) that were successfully treated with a high-flow nasal cannula (HFNC), which delivers heated, humidified gas at a fraction of inspired oxygen (FIO2) up to 1.0 (100%). Oxygenation was insufficient under non-rebreathing face masks; however, the introduction of HFNC with an FIO2 of 0.7-1.0 (flow rate: 40 L/min) improved oxygenation and was well-tolerated until the partial pressure of oxygen in blood/FIO2 ratio increased (between 21 and 26 days). Thus, HFNC might be an effective and well-tolerated therapeutic addition to the management of AEIP.Copyright © 2015 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

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