• Blood Coagul. Fibrinolysis · Jul 2009

    Case Reports

    Perioperative haemostatic management of Glanzmann thrombasthenia for abdominal surgery.

    • Susanne Lison, Michael Spannagl, and Bernhard Heindl.
    • Department of Anesthesiology, Ludwig Maximilians University of Munich, Munich, Germany. susanne.lison@med.uni-muenchen.de
    • Blood Coagul. Fibrinolysis. 2009 Jul 1;20(5):371-3.

    AbstractGlanzmann thrombasthenia is a rare congenital platelet disorder characterized by spontaneous mucocutaneous bleeding and severe bleeding complications during major surgery. This report centres on the perioperative haemostatic management of a patient with Glanzmann thrombasthenia undergoing elective major abdominal surgery. The treatment regimen was based mainly on recombinant activated factor VII, fibrinogen, and factor XIII, reducing platelet transfusion to a minimum. No red blood cell transfusions were needed perioperatively. For haemostatic monitoring, routine laboratory tests were sufficient.

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