• V Perilli, L Sollazzi, C Modesti, M G Annetta, T Sacco, M G Bocci, R M Tacchino, and R Proietti.
• Department of Anesthesiology and Intensive Care, Catholic University of Sacred Heart, Rome, Italy. perilli.v@libero.it
• Obes Surg. 2003 Aug 1;13(4):605-9.

BackgroundAnesthetized morbidly obese patients often exhibit impaired pulmonary gas exchanges, mostly because of a reduction in functional residual capacity. At present, several approaches are suggested to ventilate these patients.MethodsThe efficiency of positive end-expiratory pressure (PEEP) and reverse Trendelenburg position (RTP) were compared in order to improve oxygenation in 20 morbidly obese patients undergoing bariatric surgery.ResultsBoth PEEP and RTP determined a significant decrease in alveolar-arterial oxygen difference and an increase in total respiratory compliance (Ctot). RTP resulted in lower airway pressures than PEEP with similar improvements in Ctot and oxygenation. Concerning hemodynamic parameters, cardiac output (CO) significantly decreased with both PEEP and RTP.ConclusionsRTP and PEEP can be considered adequate ventilatory settings for morbidly obese patients, without any significant difference with regard to gas exchange improvement. However, the decrease in CO may partially counteract the beneficial effects on oxygenation of these ventilatory settings.

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