• Zh. Mikrobiol. Epidemiol. Immunobiol. · Jul 2011

    [Clinical course and outcomes of influenza A (H1N1) 2009 in pregnant women].

    • D A Tarbaeva, M P Kostinov, S A Iozefson, and E D Zagorodnyaya.
    • Zh. Mikrobiol. Epidemiol. Immunobiol. 2011 Jul 1(4):71-6.

    AimStudy of course of pregnancy, delivery, postpartum period and perinatal outcomes in pregnant women with influenza A (H1N1) 2009.Materials And MethodsCourse of pregnancy and outcomes in 16 women, who had influenza A (H1N1) 2009, were analyzed. Influenza A (H1N1) 2009 virus was detected by PCR.ResultsInfluenza A (H1N1) 2009 had a severe course and high rates of complications: pneumonia (100%), respiratory distress syndrome (25%), placental deficiency (100%). Most of the neonates (87%) from mothers, who had influenza A (H1N1) 2009, had neonatal period disorders: congenital pneumonia--2 (12.5%), cerebral ischemia--10 (62.5%), hyperbilirubinemia--2 (12.5%), vegeto-visceral syndrome--4 (25%), hemorrhagic, convulsive and respiratory distress syndrome--1 (6.7%) each. Alteration in placenta was detected--influenza placentitis. Transplacental route of virus transmission was not detected.ConclusionPregnant women are a high risk group for influenza and serious complications caused by the virus. Influenza A (H1N1) 2009 has a more severe course and a higher rate of complications in both mothers and neonates.

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