• Jaquilene Barreto da Costa, Sonia Silva Marcon, Claudia Rejane Lima de Macedo, Amaury Cesar Jorge, and Péricles Almeida Delfino Duarte.
• Hospital Universitário do Oeste do Paraná, Cascavel, PR, Brasil.
• Rev Bras Ter Intensiva. 2014 Apr 1;26(2):122-9.

ObjectiveTo investigate the relationship between sedation and the memories reported by patients subjected to mechanical ventilation following discharge from the intensive care unit.MethodsThis prospective, observational, cohort study was conducted with individuals subjected to mechanical ventilation who remained in the intensive care unit for more than 24 hours. Clinical statistics and sedation records were extracted from the participants' clinical records; the data relative to the participants' memories were collected using a specific validated instrument. Assessment was performed three months after discharge from the intensive care unit.ResultsA total of 128 individuals were assessed, most of whom (84.4%) reported recollections from their stay in the intensive care unit as predominantly a combination of real and illusory events. The participants subjected to sedation (67.2%) at deep levels (Richmond Agitation-Sedation Scale [RASS] -4 and -5) for more than two days and those with psychomotor agitation (33.6%) exhibited greater susceptibility to occurrence of illusory memories (p>0.001).ConclusionThe probability of the occurrence of illusory memories was greater among the participants who were subjected to deep sedation. Sedation seems to be an additional factor that contributed to the occurrence of illusory memories in severely ill individuals subjected to mechanical ventilation.

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