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Am J Infect Control · Mar 2009
Efficacy of an expanded ventilator bundle for the reduction of ventilator-associated pneumonia in the medical intensive care unit.
- John Blamoun, Maria Alfakir, Marie E Rella, Janice M Wojcik, Roberto A Solis, M Anees Khan, and Vincent A DeBari.
- Division of Pulmonary Medicine, School of Health and Medical Sciences, Seton Hall University, South Orange, NJ 07079, USA.
- Am J Infect Control. 2009 Mar 1;37(2):172-5.
AbstractThe ventilator bundle (VB) includes a group of clinical maneuvers (head-of-bed elevation, "sedation vacation," deep vein thrombosis prophylaxis, and peptic ulcer disease prophylaxis) to improve outcomes in patients undergoing mechanical ventilation. We modified the standard VB in our medical intensive care unit to include a group of respiratory therapist-driven protocols and, postimplementation, observed a statistically significant (P = .0006) reduction in ventilator-associated pneumonia (VAP), from a median of 14.1 cases/10(3) ventilator-days (interquartile range [IQR] = 12.1 to 20.6) to 0 cases/10(3) ventilator-days (IQR = 0 to 1.1).
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