• Anaesth Intensive Care · Apr 1999

    Incidence and predictors of central venous catheter related infection in intensive care patients.

    • S McKinley, A Mackenzie, S Finfer, R Ward, and J Penfold.
    • Intensive Care Unit, Royal North Shore Hospital, Sydney.
    • Anaesth Intensive Care. 1999 Apr 1; 27 (2): 164-9.

    AbstractThis study investigated the incidence of and risk factors for central venous catheter (CVC) infection in intensive care. CVCs were prospectively studied in patients who had lines inserted in general or neurosurgical intensive care and were expected to have the line in situ for at least 72 hours. Catheters (n = 119) were cultured for CVC-related infection (CRI; > 15 colony forming units) and blood cultures done when indicated. CRI was identified in 32 (26.9%) catheters, CVC related bacteraemia in five cases (4.2%) and CVC related sepsis in none. After adjustment for duration of catheterization, independent predictors of CVC related infection were catheter insertion site, with jugular sites having the highest risk, and primary diagnosis, with neurosurgical patients at least risk.

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