• J Neurosurg Sci · Dec 2019

    Use of gelatin haemostatic matrices in patients with intraparenchymal haemorrhage and drug-induced coagulopathy.

    • Jacopo Del Verme, Carlo Conti, and Franco Guida.
    • Department of Neurosurgery, Ospedale dell'Angelo, Mestre, Venice, Italy - j.delverme@libero.it.
    • J Neurosurg Sci. 2019 Dec 1; 63 (6): 737-742.

    AbstractIn the routine practice of neurosurgery, the attainment of appropriate hemostasis during and after surgery is of the utmost importance. In the last few years, we have noticed that in several cases the standard coagulation methods (bipolar, Tabotamp, Spongostan) were not sufficient; in particular, patients with intraparenchymal hemorrhage under anticoagulant or antiplatelet therapy were observed to be the most difficult hemostasis cases, and thus those most frequently subjected to gelatin hemostatic matrices. We report our trial on 57 patients under anticoagulant or antiplatelet therapy and with intraparenchymal hemorrhage in which gelatin hemostatic matrices were used. The excellent results both in terms of outcome and decreased bleeding allow for regarding such a practice as safe and reproducible in these cases.

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